Gr-1+CD11b+ myeloid-derived suppressor cells: Formidable partners in tumor metastasis

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Gr-1+CD11b+ Myeloid-Derived Suppressor Cells: Formidable Partners in Tumor Metastasis

The growth and metastasis of solid tumors not only depends on their ability to escape from immune surveillance but also hinges on their ability to invade the vasculature system as well as to induce the formation of new blood vessels. Gr-1(+)CD11b(+) myeloid-derived suppressor cells (MDSCs), overproduced in tumor-bearing hosts, contribute significantly to all these aspects. They also have a pote...

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ژورنال

عنوان ژورنال: Journal of Bone and Mineral Research

سال: 2010

ISSN: 0884-0431

DOI: 10.1002/jbmr.154